To show the organization of the course that includes this module, follow this link 
Course organization
The course is mostly focused on the relationship between structure and function of biological macromolecules and the main metabolic pathways in which they are involved.
The fundamental objective is to stimulate the student's interest in biomolecular science by highlighting interconnections between biochemical processes and related energetics.
At the end of the Course the student should demonstrate to have acquired the proper scientific terms and notions in order to critically and autonomously evaluate the biochemical processes of life
PROGRAM
- Structure and function of proteins: amino acids; peptide bond; structural levels of proteins; fibrous proteins and globular proteins; hemoglobin and myoglobin; hemoglobin variants; classification, function and regulation of enzymes. Chromatography
- Bioenergetics: metabolism, chemical transformations in the cell; thermodynamics; ATP as energy exchanger; oxidation/reductions.
- Structure and metabolism of carbohydrates; mono- and disaccharides; polysaccharides. Glycolysis and its regulation. Alcoholic and lactic fermentation. Gluconeogenesis. Penthose phosphate pathway. structure, function and metabolism of glycogen.
- AcetylCoA. Citric acid cycle; electron transport chain and oxidative phosphorylation; ATP synthesis.
- Structure and metabolism of lipids: structural lipids and biological membranes; lipids transport; lipids digestion and fatty acids beta-oxidation; hints on fatty acids biosynthesis
- Amino acid metabolism; transamination and oxidative deamination; urea cycle; metabolism of the carbon chain.
The frontal teaching is the exclusive method adopted in this course.
| Reference books | |||||
| Author | Title | Publisher | Year | ISBN | Note |
| M Samaja e R.Paroni | Chimica e biochimica. Per le lauree triennale dell'area biomedica | Piccin | 2016 | ||
| David L Nelson, Michael M Cox | Introduzione alla Biochimica del Lehninger | Zanichelli | 2018 | ||
| P.C. CHAMPE, R.A. HAEVEY, D.R. FERRIER | Le basi della biochimica | Zanichelli | 2015 | ||
To pass the Biochemistry module test the students must demonstrate to have acquired the comprehension and the knowledge of the program topics. Furthermore, they must show the capability to expose their reasoning in a critical and precise manner and using an appropriate scientific language.
The assessment of the subjects' learning in the Chemistry and Biochemistry modules is carried out through a joint oral test. The exam is preceded by a short written test consisting of 7 multiple-choice Chemistry Questions and 7 multiple-choice Biochemistry Questions. This test gives access to the oral exam only if the correct answers are at least five for each subject and remains valid for the entire academic year.
The final score will be expressed in thirty's (/30). The examination will be validated with a minimum score of 18/30.
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