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Daniele Dell'Orco has a long-standing experience in protein biochemistry, molecular biophysics, structural bioinformatics and systems biology. His research interests concern mostly neuronal calcium sensors and the mechanisms by which calcium sensor proteins regulate complex molecular processes, such as the phototransduction cascade in vertebrates and the mechano-transduction cascade in cochlear hair cells.
He was trained in major laboratories in Sweden, Germany and Italy and he is currently collaborating with several national and international groups. By integrating a variety of experimental and computational approaches at the system level, Daniele Dell'Orco has been investigating for many years the molecular mechanisms underlying phototransduction in retinal photoreceptors and its regulation by second messengers (Ca2+ and cGMP) under normal conditions and in those associated with genetic diseases, such as retinal dystrophies. His research is also focused on the development of biologics-based therapeutic approaches to genetic disorders affliciting sensory processes.
He has been a tenured Assistant Professor (2011) and since 2017 he is an Associate Professor of Biochemistry and Bioinformatics at the University of Verona, where he established an independent laboratory investigating several biomedical topics from a molecular perspective. He is a tutor of PhD students within the PhD programme in Biomolecular Medicine, and a supervisor of several bachelor and master undergraduate students.
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Vai al dipartimento di riferimento:
Neurosciences, Biomedicine and Movement Sciences
Skills
Topic |
Description |
Research area |
Biophysical Chemistry
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Physical and Systems Biochemistry, nanobiophysics, molecular basis of retinal diseases, protein-nanodevice interactions, structure-function properties in protein complexes, neuronal calcium sensors, bioinformatics and systems biology
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Biochemistry & Molecular Biology
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