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        Research: physiology and development  of synapses both in the central and in the peripheral nervous system.  Focus on the mechanisms of synaptic competition and elimination during development, and on the synaptic plasticity in the adult. Intracellular and patch-clamp electrophysiological techniques. Relevant findings: experimental demonstration of the importance of pattern of electric activity of motoneurons in determining the competitive outcome during the developmental process of synaptic elimination; 2) demonstration that motoneurons’ firing activity is highly synchronous at birth, and become asynchronous within 2 weeks from birth. This finding is of relevance in the process of synaptic competition. 3) experimental demonstration that the so called “silent synapses” lack of glutamatergic AMPA-type receptors.
Teaching: Human Physiology to dental students.
      
    
 
   
  
  
    
  
     
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Neurosciences, Biomedicine and Movement Sciences
              
           
       
   
    
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                	Neurophysiology
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                                Neurosciences
                              
                              
                            
                          
                        
                        
                      
                    
                  
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                	Synapse competition and plasticity
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                	Synaptic contacts are more abundant in the developing animal than in the adult. Their reduction is a process known as "synapse competition".  In the adult animal, although their overall number is stable, the synapses can modify their efficacy in many ways, a property called "synapse plasticity". Both synapse competition and synapse plasticity are processes regulated by the electrical activity of the nervous system. 
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                                Neurosciences
                              
                              
                            
                          
                        
                        
                      
                    
                  
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                - Other positions held
 
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                        - 
                          Assistant Professor
                            
                                from 11/1/02
                            
                            
                                to 2/28/10
                            
                            
                                
                            
                
                                
                                    Department in Neurological and Visual Sciences
                                    [Department deactivate from
                                    5/24/10.
                                    Confluito nel nuovo dipartimento di Scienze Neurologiche, Neuropsicologiche, Morfologiche e Motorie]
                                
                                
                                
                            
                      
 
                    
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                          Scholarship holder
                            
                                from 9/1/02
                            
                            
                                to 10/30/02
                            
                            
                                
                            
                
                                
                                    Department in Neurological and Visual Sciences
                                    [Department deactivate from
                                    5/24/10.
                                    Confluito nel nuovo dipartimento di Scienze Neurologiche, Neuropsicologiche, Morfologiche e Motorie]
                                
                                
                                
                            
                      
 
                    
                        - 
                          Assistant Professor
                            
                                from 8/1/15
                            
                            
                                to 12/31/15
                            
                            
                                
                            
                
                                
                                    Department Scienze Neurologiche Biomediche e del Movimento
                                    [Department deactivate from
                                    12/31/15.
                                    ]
                                
                                
                                
                            
                      
 
                    
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                          Assistant Professor
                            
                                from 3/1/10
                            
                            
                                to 7/31/15
                            
                            
                                
                            
                
                                
                                    Department Scienze Neurologiche e del Movimento (in dismissione dal 01/08/2015)
                                    [Department deactivate from
                                    7/31/15.
                                    ]
                                
                                
                                
                            
                      
 
                    
                      
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                        Assistant Professor
                            
                                from 1/1/03
                            
                            
                                to 12/31/19
                            
                            
                                
                            
                            
                                Faculty of
                                Medicine and Surgery