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Topic | Description | Research area |
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The autoinflammatory diseases are a heterogeneous group of diseases characterized by a genetic mutation able to modify the immune response and in particular innate immunity cells function. The clinical onset is characterized by the appearance of a continuous or sub-continuous inflammatory picture and is represented by fever, articular and/or cutaneous and/or serological involvement usually in the first years of life. | Immunology | |
Immunodeficienze primitive | Le immunodeficienze primitive sono caratterizzate da un difetto dell'immunità innata o adattativa dovuto nella maggioranza dei casi ad una mutazione genetica. Sono caratterizzate da infezioni frequenti, maggiore suscettibilità a neoplasie e possono presentarsi con malattie autoimmuni, autoinfiammatorie o allergiche. | Immunology |
Autoimmune diseases are a heterogeneous group of diseases characterized by a common triad represented by genetic predisposition, environmental influence, dysregulation of the immune system with different clinical presentation according to the different pathology. | Immunology |
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