Bachelor's degree in Speech and Language Therapy (to qualify as a speech and language therapist)

Pathophysiological science - PATOLOGIA GENERALE

Course code
Name of lecturer
Carlo Laudanna
Number of ECTS credits allocated
Academic sector
Language of instruction
LOGO 1^ ANNO - 2^ SEMESTRE dal Feb 1, 2017 al Mar 17, 2017.

To show the organization of the course that includes this module, follow this link * Course organization

Lesson timetable


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Learning outcomes

The course will develop some arguments of General Pathology preparatory to the understanding of the basic mechanisms of disease. The General Pathology comes at a critical point, the intersection between basic and clinical science. The course was aimed at establishing essential links between clinical and fundamental mechanisms, facilitating the understanding of the conceptual basis of disease.


The program in brief
They will be explained: The general concepts of illness, disease and etio-pathology; the cell-based disease; oncology elements; immunity and inflammation

Detailed program

1) Generalities

a) Introduction to general pathology: fields and discipline purposes
b) The disease: definition; causes (determinants, adjuvants, occasional); pathogenesis; course (recurrence, relapse); outcomes (healing, chronic, death); diagnosis (signs and physical examination, symptoms and medical history).

2) Cell pathology

a) General concepts: the disease as the expression of cell damage?

b) Degenerative changes of the cells:
Causes (genetic, nutritional, from chemical, physical, from lack of oxygen, by living agents).
reversible cell damage, irreversible cell death. morphological cell changes related to the damage: various aspects of degeneration and necrosis

c) Modifications to steady-state cell:
stationary phones were molecular changes (hypertrophy, atrophy, atrophy) and their causes
cellular changes (hyperplasia, hypoplasia, aplasia) and their causes

d) Alterations of cellular differentiation processes:
Metaplasia, anaplasia, dysplasia

3) Oncology

Definition of neoplastic cells, benign and malignant tumors, Natural history of cancer: advancement, growth, progress, general effects on body. Metastasis

4) Inflammation

a) General concepts: utility of the inflammatory process
b) Acute inflammation: local and general manifestations of inflammation; causes; pathogenetic mechanisms (vascular component, the white blood cell component and the chemical mediators). The exudate and types of inflammation (erythema, serous, catarrhal, purulent, fibrinous, hemorrhagic, necrotizing). The consequences on 'body (abscess, phlegmon, fistula, adhesion, synechiae, payments).
c) Chronic inflammation: Causes; pathogenetic mechanisms; granuloma and granulomatous diseases.

Reference books
Author Title Publisher Year ISBN Note
Pontieri GM Patologia e Fisiopatologia Generale per i corsi di laurea in professioni sanitarie (ristampa aggiornata) Edizioni Piccin, Padova 2007

Assessment methods and criteria

Written examination with questions with multiple answers.

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