Combined Bachelor's + Master's degree in Medicine and Surgery

Scheletal deseases in childhood  (Corso Elettivo)

Course code
0917M
Name of lecturer
Franco Antoniazzi
Coordinator
Franco Antoniazzi
Number of ECTS credits allocated
1
Academic sector
MED/38 - PAEDIATRICS
Language of instruction
Italian
Period
1° semestre dal Oct 1, 2020 al Dec 23, 2020.

Lesson timetable

Go to lesson schedule

Learning outcomes

Bringing the learners to the knowledge of skeletal pathologies in the growth phase. For this purpose, the mechanisms of growth, regulation and control of the skeleton and bone mass will be treated. Particular attention will be given to the acquisition of peak bone mass and to the genetic and epigenetic mechanisms underlying a correct skeletal development.

Syllabus

These issues will be treated specifically:
Bone growth, physiological and pathological modalities, genetic and environmental influences. Study methods.
Control of bone mass, physiological and pathological modalities, newly acquired genetic and environmental influences. Study methods.
Study of bone metabolism in Pediatrics, routine laboratory tests and in the field of research; bone apposition and resorption markers. Instrumental examinations.
Osteochondrodysplasia: pathophysiological mechanism of some childhood osteochondrodysplasias, in particular achondroplasia, dechondrosteosis, hypophosphatemic rickets, hypophosphatasia. Clinical pictures and x-rays. New diagnostic and therapeutic pathways.
Osteogenesis Imperfecta: pathogenetic mechanisms, classification of the various forms, clinical evolution, medical treatments with particular regard to bisphosphonates. New lines of research and therapeutic perspectives.
Vitamin D: Bone and extraosseous actions. Deficiency frameworks and methods of supplementation. Treatments of deficient and genetic rickets.

Reference books
Author Title Publisher Year ISBN Note
Marcadante K.J, Kliegman R.M. et al. Nelson Essential of Pediatrics (Edizione 18) Elsevier 2015

Assessment methods and criteria

Written test with 30 quizzes with multiple choice answers. For each incorrect answer, 2 points will be reduced.





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