Bachelor's degree in Biomedical Laboratory Techniques (to qualify as a biomedical laboratory worker) (Verona)

Human pathology - IMMUNOPATOLOGIA

Course code
Name of lecturer
Stefania Cane'
Number of ECTS credits allocated
Academic sector
Language of instruction
Lezioni 1anno 1 semestre TLB dal Oct 5, 2020 al Dec 4, 2020.

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Lesson timetable

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Learning outcomes

The fundamental objective of the course of immunology is the acquisition of the conceptual and scientific instruments for the understanding the function of the immune system both in healthy and disease state.
In particular the objectives are:
1. Acquisition of the knowledge of the fundamental biological mechanisms regulating the functions of the immune system during the protection against diseases.
2. Acquisition of the knowledge of pathological mechanisms affecting the immune system.
3. Description and discussion of the basic immunological assays.


Organization of the immune system:
1. Anatomy of the immune system: lymphoid organs in general (spleen, lymph nodes, Peyer patches, appendix, bone marrow and thymus).
2. Cytology of the immune system: innate immunity and acquired immunity: monocytes, neutrophils, lymphocytes, NK cells, dendritic cells. The lymphocytes classes: B and T lymphocytes and their subclasses. Antigens and antibodies.
3. Biochemistry of the immune system: molecules (Immunoglobulins, T cell receptor, MHC and costimulatory molecules).

Physiology of the immune system:
1. Antigen processing and presentation.
2. The specific adaptive responses: cell mediated immune response and humoral.
3. Cytokines and cell cooperation.
4. Defense against infections.
5. Defensive and offensive responses.
6. Active and passive immunoprophylaxis.
7. Immune tolerance.

Pathology of the immune system:
1. Hypersensibility.
2. Autoimmune diseases.
3. Immunodeficits.
4. Immunity and tumors.
5. Immuno-hematology, blood groups.
6. Immunology of transplant and HLA system.

Reference books
Author Title Publisher Year ISBN Note
Vera Del Gobbo Immunologia per le Lauree Sanitarie Piccin 2013
Jeffrey K. Actor Introduzione all'immunologia Pearson 2015
Abul K. Abbas, Andrew H. Lichtman and Shiv Pillai Le basi dell' immunologia (Fisiopatologia del sistema immunitario) (Edizione 5) Edra LSWR S.p.A. 2014 978-88-214-4255-1

Assessment methods and criteria


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