The clinical simulation has the purpose to let the students learn some organizational, technical-practical and relational skills in safe setting. Moreover clinical simulation is aiming at develop in the student the problem solving ability using case method and role-playing . Using clinical simulation may reduce the emotional impact in dealing with patents’ real situation experienced by the nursing students in clinical setting. Also, the clinical simulation offers to the students the opportunity to train and apply theoretical principles to clinical practice. The clinical simulation activity happens in equipped settings, where a tutor or an expert nurse guides a small group of students.