Pathophysiology applied at Nursing [Matricole dispari] (2020/2021)
| Teaching is organised as follows: | ||||
| Unit | Credits | Academic sector | Period | Academic staff |
| FARMACOLOGIA GENERALE | 2 | BIO/14-PHARMACOLOGY | INF VR 1° ANNO 2° SEM |
Ugo Moretti
|
| SEMEIOTICA E FISIOPATOLOGIA | 2 | MED/09-INTERNAL MEDICINE | INF VR 1° ANNO 2° SEM |
Nicola Martinelli
|
| INFERMIERISTICA CLINICA | 3 | MED/45-NURSING | See the unit page | See the unit page |
| PATOLOGIA GENERALE | 2 | MED/04-EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY | INF VR 1° ANNO 2° SEM |
Nicola Tamassia
|
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MM: FARMACOLOGIA GENERALE
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Basic principles of Pharmacology and introduction to the drugs on the market Definition of drug, active substance, pharmaceutical product, vehicle, excipient, placebo effect Evaluation of drugs efficacy: the randomized clinical trial Different sources of drugs. How drugs enter the market Bioequivalent and biosimilar drugs Italian drug market. Drugs reimbursment by the National Health Service. OTC and SOP drugs, different types of prescriptions. Package inserts: therapeutic indications, dosages, warnings and contraindications. The off-label use International classification of drugs: Anatomical Therapeutic Chemical (ATC) Classification System. How to measure drug use: the Defined Daily Dose (DDD) Pharmacodynamics Drugs classification depending on therapeutic usages. Basic principles of mechanisms of drug action: drug receptors, drug-receptor interaction: agonism and antagonism. Pharmacological, physiological and chemistry antagonisms Pharmacokinetics Drugs absorption. Main characteristics of different drug administration routes: advantages and disadvantages. Bioavailability of drugs. Food-drugs interactions Drugs distribution in the body. Carriers and efflux pumps. Factors that may influence drugs distribution: blood-brain and placental barriers Characteristics of drug metabolism. Enzyme induction and inhibition Drug clearance. Factors affecting drug clearance Definition and meaning of dose, maximum dose, daily dose, dosing, therapeutic index, clearance, half-life, peak blood levels, therapeutic range, toxic concentrations, accumulation Relationship between plasma concentrations of drugs and their action Factors to be taken into account in determining the dose of a drug, and in case of repeated administrations, dosing interval How to calculate pharmaceutical doses Pharmacotherapy Risk/benefit and cost/benefit analyses of drugs: basics. Adverse drug reactions: mechanisms and risk factors. The spontaneous reporting system of adverse drug reactions: regulation and role of nurses Antibacterial drugs: general issues and characteristics of the main classes of antibacterial drugs. Basics of antivirals and vaccines. Brief remarks on anti-cancer drugs. Non-steroidal anti-inflammatory drugs (NSAIDs): epidemiology, pharmacological mechanisms, main therapeutic uses, adverse reactions
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MM: SEMEIOTICA E FISIOPATOLOGIA
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MM: INFERMIERISTICA CLINICA
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MM: PATOLOGIA GENERALE
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Writw exam.
Mupltiple choice questions.
| Reference books | |||||
| Author | Title | Publisher | Year | ISBN | Note |
| G. M. Pontieri | Elementi di Fisiopatologia Generale | Piccin-Nuova Libraria | 2018 | 8829929085 | |
| Clayton – Stock a cura di P. Preziosi | Fondamenti di farmacologia per infermieri (Edizione 2) | EdiSeS | 2007 | 978-88-7959--402-8 | |
| Anna Brugnolli, Luisa Saiani | Medicina e infermieristica un approccio di cure integrate (Edizione 1) | Idelson Gnocchi | 2017 | 9788879476379 | |
| Saiani-Brugnolli | Trattato di cure infermieristiche (Edizione 3) | Sorbona | 2020 | 9788879477314 | |
| Singoli moduli | Vedi i libri indicati nei singoli moduli | 2019 | |||
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