Stem cell transplantation: biological and clinical issues
(Corso Elettivo)
The course aims at giving a general overview on biological features and clinical application of hematopoietic and non-hematopoietic stem cell transplantation and regenerative medicine
1) Normal bone marrow: biological bases of hematopoietic and non-hematopoietic stem cell transplantation
2) Stem cell manipulation: technical and ethical issues
3) Immunobiology of hematopoietic stem cell transplantation
a) HLA restriction and antigen presentation
b) Immune response activation, costimulation and expansion
c) Cytokine network
4) Transplant-related immunological phenomena
a) Graft-versus-Host (GvHD)
b) Graft-versus-leukaemia (GvL)
c) Host-versus-Graft (HvG)
5) Hematopoietic stem cell transplantation procedure
6) Non-hematopoietic stem cell transplantation: new frontiers in Regenerative Medicine
| Reference books | |||||
| Author | Title | Publisher | Year | ISBN | Note |
| Gian Paolo Bagnara | Cellule Staminali (Edizione 2) | Esculapio | 2013 | 978-88-7488-997-6 | |
| Robert Lanza & Anthony Atala | Essentials of Stem Cell Biology (Edizione 3) | Elsevier Scienza Publishing Fumetto INC International Concepts | 9780124095038 | ||
ATTENDANCE-BASED EVALUATION
DATE: MON 26 Oct 2020, WED 28 Oct 2020, MON 2 Nov 2020, WED 4 Nov 2020, h 17.30 - 19:30
NOTE: attendance of 3 out of 4 lessons is required for credits
Location: ONLINE LESSON VIA ZOOM (an email with the link will be sent to all subscribers 15 minutes before the start of the lesson). Credits will be given only to those who have attended at least 3 out of 4 lessons. Attendance will be recorded at each lesson, during which each student must always have the video camera on.
The course is specifically dedicated to 4th-5th-6th year students of Medicine.
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Verona University
Via dell'Artigliere 8, 37129 Verona |
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