Bachelor's degree in Biomedical Laboratory Techniques (to qualify as a biomedical laboratory worker) (Verona)

Structure and Function of Biomolecules - BIOCHIMICA

Course code
4S000330
Name of lecturer
Sofia Giovanna Mariotto
Number of ECTS credits allocated
3
Academic sector
BIO/10 - BIOCHEMISTRY
Language of instruction
Italian
Location
VERONA
Period
Lezioni TLB 1 SEMESTRE dal Oct 1, 2019 al Dec 20, 2019.

To show the organization of the course that includes this module, follow this link * Course organization

Lesson timetable

Go to lesson schedule

Learning outcomes

The course is mostly focused on the relationship between structure and function of biological macromolecules and the main metabolic pathways in which they are involved.
The fundamental objective is to stimulate the student's interest in biomolecular science by highlighting interconnections between biochemical processes and related energetics.

At the end of the Course the student should demonstrate to have acquired the proper scientific terms and notions in order to critically and autonomously evaluate the biochemical processes of life

Syllabus

- Structure and function of proteins: amino acids; peptide bond; structural levels of proteins; fibrous proteins and globular proteins; hemoglobin and myoglobin; hemoglobin variants; classification, function and regulation of enzymes. Chromatography
- Bioenergetics: metabolism, chemical transformations in the cell; thermodynamics; ATP as energy exchanger; oxidation/reductions.
- Structure and metabolism of carbohydrates; mono- and disaccharides; polysaccharides. Glycolysis and its regulation. Alcoholic and lactic fermentation.. Gluconeogenesis. Penthose phosphate pathway. structure, function and metabolism of glycogen.
- Oxidative decarboxylation of pyruvate: synthesis of AcetylCoA. Citric acid cycle; electron transport chain and oxidative phosphorylation; ATP synthesis.
- Structure and metabolism of lipids: structural lipids and biological membranes; lipids transport; lipids digestion and fatty acids beta-oxidation; hints on fatty acids biosynthesis
- Amino acid metabolism; transamination and oxidative deamination; urea cycle; metabolism of the carbon chain.

The frontal teaching is the exclusive method adopted in this course.

Reference books
Author Title Publisher Year ISBN Note
David L Nelson, Michael M Cox Introduzione alla Biochimica del Lehninger Zanichelli 2018
P.C. CHAMPE, R.A. HAEVEY, D.R. FERRIER Le basi della biochimica Zanichelli 2015

Assessment methods and criteria

To pass the Biochemistry module test the students must demonstrate to acquire the comprehension and the knowledge of the program topics. Furthermore, they must show the capability to expose their reasoning in a critical and precise manner and using an appropriate scientific language.

The assessment of the subjects' learning in the Chemistry and Biochemistry modules is carried out through a joint oral test. The exam is preceded by a short written test consisting of 7 multiple-choice Chemistry Questions and 7 Biochemistry Multiple Questions Questions. This test gives access to the oral exam only if the correct answers are at least five for each subject and remains valid for the entire academic year.

The final score will be expressed in thirty's (/30). The examination will be validated with a minimum score of 18/30.





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