Combined Bachelor's + Master's degree in Medicine and Surgery

Systematic pathology II - NEFROLOGIA

Course code
4S01146
Name of lecturers
Giovanni Gambaro, Gianluigi Zaza
Number of ECTS credits allocated
3
Academic sector
MED/14 - NEPHROLOGY
Language of instruction
Italian
Location
VERONA
Period
2° semestre 1°- 5° anno dal Feb 17, 2020 al May 29, 2020.

To show the organization of the course that includes this module, follow this link * Course organization

Lesson timetable

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Learning outcomes

The course aims to provide theoretical and practical knowledge on the etiology, pathophysiology, clinical, diagnostics and prognosis of the main diseases of the endocrine, metabolic, respiratory, cardiovascular, renal systems. Morevover, the key elements to describe and identify the pathologic features correlated to the above disorders will be presented.

Syllabus

RENAL PHYSIOLOGY
DIAGNOSTIC ELEMENTS OF NEFROPATIES
- Evaluation of renal function (glomerular filtration, tubular function, renal blood flow)
- Urine Examination
Signs and symptoms of the disorders
- Nephrology syndromes
- Instrumental Investigations (Ultrasound, Radiological Investigations, Radioisotopic Investigations)
- Renal Biopsy
GLOMERULAR DISEASES
- Classification
- Ethiopathogenesis
- Main anatomy-clinical pictures of primary glomerular nephropathy
- Nephrotic syndrome (causes, pathophysiology, complications)
- Nephritic syndrome (causes, pathophysiology, complications)
- Rapidly progressive glomerulonephritis (etiopathogenesis, anatomoclinic framework)
- Secondary and hereditary glomerular nephropathy
VASCULAR NEPHROPATHIES
- Thrombosis of the renal vein
- Renal infarction, cholesterol microembolization
- Renal artery stenosis (nephrovascular hypertension): etiopathogenesis, pathophysiology, diagnostics)
- Nephroangiosclerosis
- Vasculitis (classification, etiopathogenesis, anatomic-clinical presentations)
- Thrombotic microangiopathy
TUBULO-INTERSTITIAL NEPHROPATIES
- Acute interstitial nephritis (etiopathogenesis, anatomic-clinical presentations)
- Chronic interstitial nephritis (classification, etiopathogenesis, anatomic-clinical presentations)
- Reflux nephropathy (etiopathogenesis, anatomic-clinical picture, diagnostics)
INFECTION OF THE RIBBON AND THE URINARY VIEWS
- Acute pyelonephritis (etiopathogenesis, anatomic-clinical picture)
- Chronic Pyelonephritis (etiopathogenesis, anatomic-clinical picture)
- Renal tuberculosis (etiopathogenesis, anatomic-clinical picture)
RENAL CALCULI
- Classification
- Etiopathogenesis
- Diagnostic and clinical elements
MALPHORMATIVE, DYSPLASTIC AND CYSTIC NEFROPATIES
- Embryology of the kidney and urinary tract
- Abnormal shape, number and position of the kidney
- Renal dysplasia
- Cystic diseases: simple cysts, dysplastic cysts, polycystic kidney, medullary sponge kidney, nephronophthisis (etiopathogenesis, anatomic-clinical pictures, diagnostics)
ACUTE RENAL FAILURE AND ACUTE KIDNEY INJURY
- Classification
- Ethiopathogenesis
- Diagnostic and clinical elements
CHRONIC RENAL FAILURE
- Cause
- Pathophysiology
- Metabolic changes
- Clinical features, treatment and replacement therapy (hemodialysis, peritoneal dialysis, renal transplantation)
THE KIDNEY IN PREGNANCY
- Physiological adaptation of the kidney to pregnancy
- Hypertensive disorders of pregnancy
THE KIDNEY IN THE ELDER
- Pathophysiology of renal senescence

















































































































RENAL PHYSIOLOGY
DIAGNOSTIC ELEMENTS OF NEPHROPATIES
- Evaluation of renal function (glomerular filtration, tubular function, renal blood flow)
- Evaluation of Urine Examination
Signs and symptoms of the disorder
- Nephrology syndromes
- Instrumental Investigations (Ultrasound, Radiological Investigations, Radioisotopic Investigations)
- Renal Biopsy
GLOMERURAL DISEASES
- Classification
- Ethiopathogenesis
- Main anatomy-clinical pictures of primitive glomerular nephropathy
- Nephrotic syndrome (causes, pathophysiology, complications)
- Nephritic syndrome (causes, pathophysiology, complications)
- Rapidly progressive glomerulonephritis (etiopathogenesis, anatomo clinic framework)
- Secondary and hereditary glomerular nephropathy (lupus nephritis, cryogenic nephritis,
Diabetic nephropathy, pregnancy purpura, Alport syndrome)
VASCULAR NEPHROPATIES
- Thrombosis of the renal vein
- Renal failure
- Renal artery stenosis (nephrovascular hypertension): ethiopathogenesis, pathophysiology, diagnostics)
- Nephroangiosclerosis
- Vasculitis (classification, ethiopathogenesis, pathology and clinical aspects)
- Thrombotic microangiopathy
TUBULOUS-INTERSTITIAL NEPHROPATIES
- Acute interstitial nephritis (ethiopathogenesis, anatomic-clinical picture)
- Chronic interstitial nephritis (classification, ethiopathogenesis, anatomic-clinical frameworks)
- Reflux nephropathy (ethiopathogenesis, anatomic-clinical picture, diagnostics)
INFECTIONS and KNIDNEY
- Acute pielonephritis (ethiopathogenesis, anatomic-clinical picture)
- Chronic Pielonephritis (ethiopathogenesis, anatomic-clinical picture)
- Renal tuberculosis (ethiopathogenesis, anatomic-clinical picture)
RENAL STONES
- Classification
- Ethiopathogenesis
- Diagnostic and clinical elements
MALFORMATIVE NEPHROPATIES
- Abnormal shape, number and position of the kidney
- Renal dysplasia
- Cystic cystic diseases: simple cysts, dysplastic cysts, polycystic kidney, sponge kidney,
ACUTE RENAL INSUFFICIENCY
- Classification
- Ethiopathogenesis
- Diagnostic and clinical elements
CHRONIC RENAL FAILURE
- Cause
- Physiopathology
- Metabolic changes
- Clinical features and therapy
PREGNANCY and KIDNEY
AGING KIDNEY








Reference books
Author Title Publisher Year ISBN Note
Dennis L. Kasper, Eugene Braunwald, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson Harrison - Principi di Medicina Interna.2 voll. (Edizione 19) McGraw-Hill, Milano 2015
Francesco Paolo Schena, Francesco Paolo Selvaggi, Loreto Gesualdo, Michele Battaglia Malattie del rene e delle vie urinarie (Edizione 4) McGraw Hill 2008 9788838623974
Garibotto - Pontremoli - Biancone - AAVV Manuale di nefrologia (Edizione 2) Minerva Medica 2017 9788877118868

Assessment methods and criteria

Oral. The student will answer to 3-4 questions regarding specific nephrology topics.





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