Genetics and Molecular Biology - BIOLOGIA MOLECOLARE
To show the organization of the course that includes this module, follow this link 
Course organization
To understand the fundamental processes of the science of DNA and the flow of information that leads from DNA to RNA to proteins.
To understand mechanisms, function and regulation of these processes.
To educate medical students to the scientific method through the description of experiments that allowed the elucidation of molecular biological mechanisms.
To understand recombinant DNA technologies and their potential.
Upon completing the course, students will be able to understand the main molecular mechanisms underlying the regulation of gene expression and how these knowledge can be applied in the field of modern biomedicine.
• Structure and conformations of DNA
• Complexity of genomic DNA • DNA structure in chromosomes • DNA replication
• DNA repair
• Recombination
• Transcription in prokaryotes and eukaryotes
• Maturation of RNA
• Genetic Code
• Translation
• Regulation of gene expression in prokaryotes
• Regulation of gene expression in eukaryotes
• Degradation and trafficking of proteins
• DNA recombinant technology and recombinant DNA
• Molecular evolution
• An outline of gene therapy
| Reference books | |||||
| Author | Title | Publisher | Year | ISBN | Note |
| Michael Cox | Biologia Molecolare | Zanichelli | 2013 | ||
| Amaldi, Benedetti, Pesole, Plevani | Biologia Molecolare (Edizione 3) | Ambrosiana | 2018 | 978-88-08-18518-1 | |
| R. F. Weaver | Biologia Molecolare (Edizione 2) | McGraw Hill | 2009 | 978-88-386-6507-3 | |
| WATSON James D , BAKER Tania A , BELL Stephen P , GANN Alexander , LEVINE Michael , LOSICK Richard | Biologia molecolare del gene (Edizione 7) | Zanichelli | 2015 | 978-88-08-36480-7 | |
The exam consists of a written test containing 30 multiple-choice questions.
There is also an open question to which the student should anser in a concise, precise, clear and organic way.
Students who will pass the written test will be admitted to a short oral exam, during which topics related to the course will be discussed.
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