Combined Bachelor's + Master's degree in Medicine and Surgery

Genetics and Molecular Biology - BIOLOGIA MOLECOLARE

Course code
Name of lecturer
Donato Zipeto
Number of ECTS credits allocated
Academic sector
Language of instruction
1° semestre dal Sep 30, 2019 al Jan 10, 2020.

To show the organization of the course that includes this module, follow this link * Course organization

Lesson timetable

Go to lesson schedule

Learning outcomes

To understand the fundamental processes of the science of DNA and the flow of information that leads from DNA to RNA to proteins.
To understand mechanisms, function and regulation of these processes.
To educate medical students to the scientific method through the description of experiments that allowed the elucidation of molecular biological mechanisms.
To understand recombinant DNA technologies and their potential.

Upon completing the course, students will be able to understand the main molecular mechanisms underlying the regulation of gene expression and how these knowledge can be applied in the field of modern biomedicine.


• Structure and conformations of DNA
• Complexity of genomic DNA • DNA structure in chromosomes • DNA replication
• DNA repair
• Recombination
• Transcription in prokaryotes and eukaryotes
• Maturation of RNA
• Genetic Code
• Translation
• Regulation of gene expression in prokaryotes
• Regulation of gene expression in eukaryotes
• Degradation and trafficking of proteins
• DNA recombinant technology and recombinant DNA
• Molecular evolution
• An outline of gene therapy

Reference books
Author Title Publisher Year ISBN Note
Michael Cox Biologia Molecolare Zanichelli 2013
Amaldi, Benedetti, Pesole, Plevani Biologia Molecolare (Edizione 3) Ambrosiana 2018 978-88-08-18518-1
R. F. Weaver Biologia Molecolare (Edizione 2) McGraw Hill 2009 978-88-386-6507-3
WATSON James D , BAKER Tania A , BELL Stephen P , GANN Alexander , LEVINE Michael , LOSICK Richard Biologia molecolare del gene (Edizione 7) Zanichelli 2015 978-88-08-36480-7

Assessment methods and criteria

The exam consists of a written test containing 30 multiple-choice questions.
There is also an open question to which the student should anser in a concise, precise, clear and organic way.
Students who will pass the written test will be admitted to a short oral exam, during which topics related to the course will be discussed.

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