The course aims at giving a general overview on biological features and clinical application of hematopoietic and non-hematopoietic stem cell transplantation and regenerative medicine
1) Normal bone marrow: biological bases of hematopoietic and non-hematopoietic stem cell transplantation
2) Stem cell manipulation: technical and ethical issues
3) Immunobiology of hematopoietic stem cell transplantation
a) HLA restriction and antigen presentation
b) Immune response activation, costimulation and expansion
c) Cytokine network
4) Transplant-related immunological phenomena
a) Graft-versus-Host (GvHD)
b) Graft-versus-leukaemia (GvL)
c) Host-versus-Graft (HvG)
5) Hematopoietic stem cell transplantation procedure
6) Non-hematopoietic stem cell transplantation: new frontiers in Regenerative Medicine
| Reference books | |||||
| Author | Title | Publisher | Year | ISBN | Note |
| Gian Paolo Bagnara | Cellule Staminali (Edizione 2) | Esculapio | 2013 | 978-88-7488-997-6 | |
| Robert Lanza & Anthony Atala | Essentials of Stem Cell Biology (Edizione 3) | Elsevier Scienza Publishing Fumetto INC International Concepts | 9780124095038 | ||
| S. Tura | LEZIONI DI EMATOLOGIA | 6° edizione - Società Editrice Esculapio, Bologna | 2015 | ||
| Paolo Corradini - Robin Foà | Manuale di ematologia | Minerva Medica | 2014 | 8877118164 | |
ATTENDANCE-BASED EVALUATION
DATE: MON 28 Oct 2019, THU 31 Oct 2019, MON 4 Nov 2019, WED 6 Nov 2019, h 17.30 - 19:30
NOTE: attendance of 3 out of 4 lessons is required for credits
Location: TBD
The course is specifically dedicated to 4th-5th-6th year students of Medicine.
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Verona University
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