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Students will acquire the fundamental notions about the life functions of healthy human beings, in order to understand the working of their organs and systems, of their regulation mechanisms and the main processes of integration and homeostatic control.
Principles of cell functions. Homeostasis of body fluids. Signal transduction - membrane receptors, second messengers and regulation of gene expression.
Membrane potential. Graduate potentials. Action potential.
Classification of neural fibers.
Electrical and chemical synapses. Neurotransmitters and hormones.
Sensory systems - Receptors and signal transduction. Receptors and afferent fibers for the processing of visual, auditory, tactile, proprioceptive, thermal and noxious stimuli. Central processing of sensory inputs. Pain.
Motor systems - Neuromuscular junction. Spinal reflexes.
Autonomous nervous system - Functional organization.
Skeletal muscle- Functional organization. Structural and functional bases of muscle contraction. Classification of muscle fibers. Motor units.
Smooth muscle and cardiac muscle.
Circulation. Elements of cardiac function. Regulation of heart and vasculature. Integrated control of the cardiovascular system.
Structure and function of the respiratory system. Static and dynamic mechanical properties of the lung and chest wall.
Ventilation, perfusion and their relationships. Oxygen and carbon dioxide transport. Control of respiration. Non-respiratory functions of the lung.
The gastrointestinal tract. Integrated responses to a meal: Cephalic, oral, esophageal, gastric and small intestinal and colonic phases. Transport and metabolic functions of the liver.
Solute and water transport along the nephron: tubular function. Control of body fluid osmolality and volume. Potassium, calcium and phosphate homeostasis. Role of the kidneys in the regulation of acid-base balance.
ENDOCRINE AND REPRODUCTIVE SYSTEMS
Hormonal regulation of energy metabolism. Hormonal regulation of calcium and phosphate metabolism. Hypothalamus and pituitary gland. Thyroid glands. Adrenal glands. Male and female reproductive systems.
|Silverthorn||Fisiologia umana. Un approccio integrato||Pearson||2020||8891902179|
Written exam, with multiple choice questions.