Combined Bachelor's + Master's degree in Medicine and Surgery

Clinical Pharmacology

Course code
Name of lecturer
Guido Francesco Fumagalli
Guido Francesco Fumagalli
Number of ECTS credits allocated
Academic sector
Language of instruction
Lezioni 1° semestre 2°- 6° anno dal Oct 3, 2016 al Dec 22, 2016.

Lesson timetable

Lezioni 1° semestre 2°- 6° anno

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Learning outcomes

This course is an expansion/continuation of the General Pharnmacology course. By completing this course, the student will:
- Know the properties (mechanisms of action, clinical effects, pharmacokinetics, therapeutic uses, adverse reactions) of classes of drugs active on: cardiovascular, central and peripheral, endocrine, and gastrointestinal systems and acting on inflammatory processes.
- Be able to define the rationale for the selection and use of drug in relation to the undergoing pathology, the characteristics and the clinical state of the patient and the evidences available on the scientific literature
- Know how to monitor the efficacy of the therapy and recognize the occurrence of adverse reactions.


The programme of the course is focussed on the analysis of drug properties (mechanism of action, clinical effects, therapeutic use, adverse reaction). Specifically, for each class of drugs, the student will:
Know the level of evidence and the classification of recommendation as defined by the scientific literature and the referring medical scientific association
Recognize the efficacy of a drug/therapy based on positive symptoms elicited and the occurrence of adverse reactions
Construct the rationale for the therapeutic choices based on the properties of drugs actives on cardiovascular, central and peripheral, endocrine, and gastrointestinal systems and acting on inflammatory processes.
Know how to use manuals and write prescriptions
Be able to critically understand design and results of clinical trials
The classes of drugs that will be considered are the following:
Drugs active on cardiovascular system
Drugs active on Central and Peripheral Nervous system
Drugs active on gastrointestinal tract
Drugs for the control of dislipidemia
Oral antidiabetic drugs
Drugs active on inflammatory processes

Reference books
Author Title Publisher Year ISBN Note
Bertram G. Katzung Basic and Clinical Pharmacology (Edizione 13) McGraw-Hill Education 2015 978-0-07-182505-3
B. G. Katzung & A. J. Trevor Farmacologia Generale e Clinica (Edizione 10) Piccin-Nuova Libraria 2017 978-88-299-2847-7
Goodman & Gilman The pharmacological basis of therapeutics (Edizione 13) McGraw-Hill Education 2017 9780071624428

Assessment methods and criteria

Oral examination
The student will be asked to describe the properties of classes of drugs, mentioning the mechanisms of action, the clinical effects, the therpeutic indication; the limits of the therapy and the most relevat adverse reactions;, the criteria of selection between drugs of a same classe or between different classes


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