Bachelor's degree in Cardiocirculatory Physiopathology and Cardiovascular Perfusion Techniques (national qualification)

General pathology and pharmacology - PATOLOGIA GENERALE

Course code
4S01610
Name of lecturer
Patrizia Scapini
Number of ECTS credits allocated
2
Other available courses
Academic sector
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
Language of instruction
Italian
Location
VERONA
Period
Lezioni PERF 2 SEMESTRE dal Mar 2, 2020 al May 15, 2020.

To show the organization of the course that includes this module, follow this link * Course organization

Lesson timetable

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Learning outcomes

The student must acquire knowledge of the mechanisms of cellular and molecular damage and of the pathogenetic processes and mechanisms of reaction to restore health. The main training objectives are:
• understanding of the mechanisms of cellular and molecular damage;
• learn about reactions to biological damage which are crucial in the process of healing/repair or pathology, with an emphasis on mechanisms of immunity, inflammation, wound healing and chronic biological processes;
• gain knowledge of scientific terms and language that are used in medical practice in order to effectively communicate with other health care professionals.

Syllabus

I. Introduction:
- general concepts
- the pathological process as an alteration of homeostasis
- adaptation, compensation and responsiveness
- pathogenesis
- etiology
II. Cellular Pathology:
-cell death: necrosis and apoptosis
- pathogenetic processes implicated in cellular damage
III. Natural immunity and acquired immunity:
- innate immune cells
- adaptive immune cells
IV. Tissue responses to cell damage:
- acute inflammation: changes in flow and vascular permeability;
- inflammatory exudates (types, composition, localization);
- mechanisms controlling phagocyte migration to the inflammatory sites
- effector functions of phagocytes: oxygen-dependent and oxygen-independent bactericidal mechanisms, phagocytosis
V. Mediators of acute inflammation: plasma-derived mediators and cell-derived mediators
- coagulation system, complement system, vasoactive amines
- cytokines
VI. Evolution of the acute inflammatory response:
-tissue repair, regeneration and fibrosis
-chronic inflammation: chronic systemic diseases (ex. granuloma)
VII. Neoplasms

Reference books
Author Title Publisher Year ISBN Note
Pontieri G.M. Elementi di Patologia generale Piccin 2018
Emanuel Rubin, Howard M. Reisner Patologia Generale. L'essenziale Piccin 2015 978-88-299-2740-1

Assessment methods and criteria

The assignment of General Pathology consists of a written test with 21 multiple choice questions.
The evaluation criteria are the following: 1,5 points for correct answers; 0,75 points for partially correct answers; 0 points for missing/wrong answers.
The exam in considered valid when the student achieves a minimal overall grade of 18 points.





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