Bachelor's degree in Environmental and Workplace Accident Prevention Techniques (national qualification) (Trento)

Biomedical sciences and action of risk factors - PATOLOGIA GENERALE

Course code
4S000469
Name of lecturer
Patrizia Scapini
Number of ECTS credits allocated
2
Academic sector
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
Language of instruction
Italian
Period
TPALL 1° ANNO 1° SEMESTRE dal Oct 1, 2019 al Dec 20, 2019.

To show the organization of the course that includes this module, follow this link * Course organization

Lesson timetable

Go to lesson schedule

Learning outcomes

The student must acquire knowledge of the mechanisms of cellular and molecular damage and of the pathogenetic processes and mechanisms of reaction to restore health. The main training objectives are:
• understanding of the mechanisms of cellular and molecular damage;
• learn about reactions to biological damage which are crucial in the process of healing/repair or pathology, with an emphasis on mechanisms of immunity, inflammation, wound healing and chronic biological processes;
• gain knowledge of scientific terms and language that are used in medical practice in order to effectively communicate with other health care professionals.

Syllabus

I. Introduction:
- general concepts
- the pathological process as an alteration of homeostasis
- adaptation, compensation and responsiveness
- pathogenesis
- etiology
II. Cellular Pathology:
-cell death: necrosis and apoptosis
- pathogenetic processes implicated in cellular damage
- Main concepts of Environmental Pathology: physical agents (mechanical energy, electrical current, heat, radiation, chemical agents) as causes of disease.
III. Natural immunity and acquired immunity:
- innate immune cells
- adaptive immune cells
IV. Tissue responses to cell damage:
- acute inflammation: changes in flow and vascular permeability;
- inflammatory exudates (types, composition, localization);
- mechanisms controlling phagocyte migration to the inflammatory sites
- effector functions of phagocytes: oxygen-dependent and oxygen-independent bactericidal mechanisms, phagocytosis
V. Mediators of acute inflammation: plasma-derived mediators and cell-derived mediators
- coagulation system, complement system, vasoactive amines
- cytokines
VI. Evolution of the acute inflammatory response:
-tissue repair, regeneration and fibrosis
-chronic inflammation
VII. Neoplasms

Reference books
Author Title Publisher Year ISBN Note
Pontieri G.M. Elementi di Patologia generale Piccin 2018
Emanuel Rubin, Howard M. Reisner Patologia Generale. L'essenziale Piccin 2015 978-88-299-2740-1

Assessment methods and criteria

The evaluation is performed as a written test within the exam of PATHOLOGY (visit also the assessment methods and criteria reported on the general web page of the course).
The assignment of General Pathology consists of a written test with 21 multiple choice questions.
The evaluation criteria are the following: 1,5 points for correct answers; 0,75 points for partially correct answers; 0 points for missing/wrong answers.
A positive evaluation is reached when the student achieves a minimal overall grade of 18 points.





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