Bachelor's degree in Cardiocirculatory Physiopathology and Cardiovascular Perfusion Techniques (national qualification)

General pathology and pharmacology - FARMACOLOGIA GENERALE

Course code
4S01610
Name of lecturer
Guido Francesco Fumagalli
Number of ECTS credits allocated
2
Academic sector
BIO/14 - PHARMACOLOGY
Language of instruction
Italian
Period
Lezioni PERF 2 SEMESTRE dal Mar 2, 2020 al May 15, 2020.

To show the organization of the course that includes this module, follow this link * Course organization

Lesson timetable

Go to lesson schedule

Learning outcomes

General aims:
Learn the conceptual basis of drug mechanisms of actions in order to understand how physio-pathological events in patients can be modified by therapeutic approaches and how drugs and physiotherapy may interact on a same subject
Know the mechanisms of action, the effects, the adverse reaction and the therapeutic significance of classes of drugs relevant in cardiology

Specific aims:
Goal of this module is to provide the student with the scientific knowledge required to:
• Understand the mechanisms of action of drugs responsible of their beneficial and adverse effects,
• Learn how clinical evaluation is applied to the study and industrial development of drugs,
• Know the rules governing drug-cell interaction and pharmacokinetics.
• Understand the rules of a rational approach to therapy
• Know the effects and the clinical use of the classes of drugs active on the cardiovascular system and relevant in the specific professional context.

Syllabus

Programme of the course
 Drug-receptor interactions, effect generation and mechanisms of adaptation to drug action; relevant terminology in clinical settings and basic aspects of clinical studies of drugs.
 Pharmacokinetics: ADME, differences between routes of absorption, terminology and most relevant pharmacokinetic parameters. Modification of therapeutic protocols due to diseases, other drugs, genetics and nutrients
 Mechanisms of action, therapeutic and adverse effects, indication and mode of use of inotropic agents (cardiac glicosides; PDE inhibitors; dobutamine, dopamine)
 Mechanisms of action, therapeutic and adverse effects, indication and mode of use of ACEi inhibitors and ARB/sartans
 Mechanisms of action, therapeutic and adverse effects, indication and mode of use of diuretic agents
 Mechanisms of action, therapeutic and adverse effects, indication and mode of use of vasodilators: nitrates and calcium antagonists
 Mechanisms of action, therapeutic and adverse effects, indication and mode of use of anticoagulant and antiaggregant drugs (NSAIDS)
 Mechanisms of action, therapeutic and adverse effects, indication and mode of use of agents used for the treatment of hyperlipoproteinemias

Reference books
Author Title Publisher Year ISBN Note
F. Rossi, V. Cuomo, C. Riccardi Farmacologia (Edizione 3) Minerva Medica 2017 978-88-7711-881-3
A. Conforti, L. Cuzzolin, R. Leone, U. Moretti, G. Pignataro, M. Taglialatela, M. Vanzetta Farmacologia per le professioni sanitarie (Edizione 1) Idelson-Gnocchi 2015 978-88-7947-592-1

Assessment methods and criteria

Written exam with 32 multiple choice questions

Evaluation: 1 point for correct answer, 0 for missing/wrong answer





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