Combined Bachelor's + Master's degree in Dentistry and Dental Prosthetics

Medical sciences 1st (2018/2019)

Course code
4S02657
Credits
14
Coordinator
Lucia De Franceschi

Teaching is organised as follows:
Unit Credits Academic sector Period Academic staff
MEDICINA INTERNA 6 MED/09-INTERNAL MEDICINE LEZIONI 1° SEMESTRE 2°-3°-4°-5°-6° ANNO Lucia De Franceschi
MEDICINA DI LABORATORIO 3 BIO/12-CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY LEZIONI 1° SEMESTRE 2°-3°-4°-5°-6° ANNO Elisa Danese
MALATTIE DELL'APPARATO VISIVO 2 MED/30-OPHTHALMOLOGY LEZIONI 1° SEMESTRE 2°-3°-4°-5°-6° ANNO Giorgio Marchini
ATTIVITA' PRATICA IN MEDICINA INTERNA 1 NN-- LEZIONI 1° SEMESTRE 2°-3°-4°-5°-6° ANNO Lucia De Franceschi
ATTIVITA' PRATICA IN MEDICINA DI LABORATORIO 2 NN-- LEZIONI 1° SEMESTRE 2°-3°-4°-5°-6° ANNO Elisa Danese

Learning outcomes

The present course has been designed to provide fundamental knowledge about pathophysiology, clinical, diagnostic classification and therapy of diseases of relevance of Internal Medicine with particular regard to those pathologies that may present clinical manifestations also at the level of the oral cavity and / or may be connected to the dental preservative treatment or maxillofacial surgery. It is also aimed to generate knowledge about the general prerequisites and criteria for the interpretation of laboratory tests based on the concepts of normality, reference intervals, analytic and biological intra- and inter-individual variability. At the end of the course students will be able to interpret the diagnostic value of laboratory tests, in terms of specificity, sensitivity, positive and negative predictive value.
MODULO MEDICINA INTERNA
The course is aimed to discuss and generate knowledge on internal medicine diseases, focusing on those with clinical manifestations involving mouth, neck/head. Pathophysiology, clinical presentation and complications of internal medicine disorders is part of the course.
MODULO ATTIVITA’ PRATICA IN MEDICINA INTERNA
Main objective: • To gain experience of patient history collection and patient clinical evaluation • To learn to assess main medical problems in internal medicine patients (acute and chronic diseases) • To learn the management of emergency in internal medicine such as acute respiratory failure, cardiac arrest.
MODULO MEDICINA DI LABORATORIO e MODULO ATTIVITA’ PRATICA IN MEDICINA DI LABORATORIO Educational goals. At the end of the course the student will: 1) Know the general prerequisites and criteria for the interpretation of laboratory tests based on the concepts of normality, reference intervals, analytic and biological intra- and inter-individual variability. Will be able to interpret the diagnostic value of laboratory tests, in terms of specificity, sensitivity, positive and negative predictive value. 2) Will know the basic principles of laboratory methodologies in the pre-analytical phase (sampling, treatment and storage of samples), analytical phase (principles and implementation of the most important laboratory techniques), and post-analytical phase (collection, processing and reporting of data, interpretation of results, quality control). 3) Will know the pathophysiological meaning underlying the alterations of laboratory indexes and will integrate these alterations with the signs and symptoms clinically detected by the anamnesis and by the objective examination to arrive at a diagnostic interpretation of the most important clinical syndromes. 4) On the basis of the physiopathological and clinical significance of laboratory tests, the student will be able to understand the motivations of the exam requests, the logical operativity and the semiologic value of the individual tests in a typical clinical series.
MODULO MALATTIE DELL’APPARATO VISIVO
At the end of this course the student should be able to: -Describe the anatomy and the physiopathology of the orbit and the adnexa (exophthalmos, inflammations and tumours of the orbit, pathology of the eyelids and of the lacrimal system, orbital trauma) -Describe the anatomy, physiopathology and the pathology of the conjunctiva, sclera, uvea, lens and posterior segment -Describe the physiopathology of the hydrodynamics of aqueous humour (Glaucoma) -Describe the physiopathology of the optic nerve and optic ways, eye refraction defects and of some pathologies of infancy.

Syllabus

The program of the course is divided into the following sections:
Internal Medicine
Collection of patient history and clinical evaluation;
General concepts of laboratory in internal medicine disorders;
Hematology. Anemias, disorders of coagulation and thrombocytopenias, main and most common myeloproliferative disorders, lymphomas, bone marrow transplantation (acute and chronic complication such as GVDH);
Cardiology. Ischemic cardiomyopathy and acute heart infarction, left heart failure;
Shock
Endocarditis and valve heart diseases;
Hypertension
Pneumology. Pneumonias, pulmonary thromboembolism, COPD, acute and chronic bronchitis;
Nephrology: acute and chronic kidney disease;
Endocrinology. Diabetes, thyropathies (hyper/hypo); parathyroid diseases; adrenal gland diseases (i.e.: hyperaldosternism);
Reumathology. Main rheumatologic disease with complications involving mouth: RA, LES, Syogren S, Systemic sclerosis, Bechet disease, vasculitis;
Gastroenterology. (i) Main disorders of the esophagus, stomach in particular acute/chronic gastritis, HPP infection and related complications; (ii) malabsorption and coeliac disease; (iii) chronic bowel inflammatory diseases; (iv) hepatic cirrhosis;
Principles of infectious diseases important in dental care. HBV-HCV hepatitis, AIDS, herpes virus and tuberculosis.

Laboratory of Medicine
Pre-analytical variability
Analytical variability. Enzymes in diagnosis and disease monitoring
Hepatic function
Post analytical variability. Interpretation of laboratory data
Tumor markers
Hemocromocytometric examination
Laboratory tests in primary hemostasis
Laboratory tests in secondary hemostasis
The anticoagulation theraphy monitoring
Plasma proteins and inflammatory indices. Renal function
Diabetes
laboratory testing in the diagnosis and management of thyroid disorders

Ophthalmology

Assessment methods and criteria

Assessment methods and criteria
Internal Medicine
The exam is divided into 2 steps:
There is a multi-choice test followed by oral exam for those who reach 18/30 score.
Laboratory of Medicine
Written, using structured text in multiple questions, short integrated clinical cases with responses, interpretation of laboratory data.
Ophthalmology

Reference books
Author Title Publisher Year ISBN Note
C. Rugarli Medicina Interna Sistematica MASSON 2016
Angelo Raffaele Bianco, Sabino De Placido, Giampaolo Tortora e Pierfranco Conte Oncologia Clinica 2/ed (Edizione 2) McGraw-Hill Education (Italy) srl 2016 9788838639845
Ciaccio M, Lippi G Biochimica Clinica e Medicina di Laboratorio (Edizione 2017) EdiSES Edizioni Scientifiche ed Universitarie 2017 9788879599580
Amoroso A, Costantino S, Afeltra A, Picardi A, Vettore L. Semeiotica pratica. Sussidio multimediale per l’apprendimento e la verifica delle principali manovre semeiologiche. Centro Scientifico Editore 2005




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