Bachelor's degree in Nursing (to qualify as a nurse) (Verona)

Pathophysiology applied at Nursing [Matricole dispari] (2018/2019)

Course code
4S000090
Credits
9
Coordinator
Roberto Leone

Teaching is organised as follows:
Unit Credits Academic sector Period Academic staff
FARMACOLOGIA GENERALE 2 BIO/14-PHARMACOLOGY INF VR - 1° anno 2° sem Roberto Leone
SEMEIOTICA E FISIOPATOLOGIA 2 MED/09-INTERNAL MEDICINE INF VR - 1° anno 2° sem Antonio Carletto
INFERMIERISTICA CLINICA 3 MED/45-NURSING See the unit page See the unit page
PATOLOGIA GENERALE 2 MED/04-EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY INF VR - 1° anno 2° sem Barbara Rossi

Learning outcomes

The course introduces the student to the understanding of the basic concepts concerning the main diseases and the fundamental pathogenic processes, correlating them to the cellular alterations, of the organ function, of the homeostatic mechanisms, and to the clinical manifestations of the disease.
It also aims to develop an approach oriented to the definition of problems and interventions with regard to the main alterations of respiratory and elimination functions, and multidimensional assessment of pain.

Syllabus

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MM: FARMACOLOGIA GENERALE
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Basic principles of Pharmacology and introduction to the drugs on the market Definition of drug, active substance, pharmaceutical product, vehicle, excipient, placebo effect Evaluation of drugs efficacy: the randomized clinical trial Different sources of drugs. How drugs enter the market Bioequivalent and biosimilar drugs Italian drug market. Drugs reimbursment by the National Health Service. OTC and SOP drugs, different types of prescriptions. Package inserts: therapeutic indications, dosages, warnings and contraindications. The off-label use International classification of drugs: Anatomical Therapeutic Chemical (ATC) Classification System. How to measure drug use: the Defined Daily Dose (DDD) Pharmacodynamics Drugs classification depending on therapeutic usages. Basic principles of mechanisms of drug action: drug receptors, drug-receptor interaction: agonism and antagonism. Pharmacological, physiological and chemistry antagonisms Pharmacokinetics Drugs absorption. Main characteristics of different drug administration routes: advantages and disadvantages. Bioavailability of drugs. Food-drugs interactions Drugs distribution in the body. Carriers and efflux pumps. Factors that may influence drugs distribution: blood-brain and placental barriers Characteristics of drug metabolism. Enzyme induction and inhibition Drug clearance. Factors affecting drug clearance Definition and meaning of dose, maximum dose, daily dose, dosing, therapeutic index, clearance, half-life, peak blood levels, therapeutic range, toxic concentrations, accumulation Relationship between plasma concentrations of drugs and their action Factors to be taken into account in determining the dose of a drug, and in case of repeated administrations, dosing interval How to calculate pharmaceutical doses Pharmacotherapy Risk/benefit and cost/benefit analyses of drugs: basics. Adverse drug reactions: mechanisms and risk factors. The spontaneous reporting system of adverse drug reactions: regulation and role of nurses Antibacterial drugs: general issues and characteristics of the main classes of antibacterial drugs. Basics of antivirals and vaccines. Brief remarks on anti-cancer drugs. Non-steroidal anti-inflammatory drugs (NSAIDs): epidemiology, pharmacological mechanisms, main therapeutic uses, adverse reactions
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MM: SEMEIOTICA E FISIOPATOLOGIA
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MM: INFERMIERISTICA CLINICA
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MM: PATOLOGIA GENERALE
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Assessment methods and criteria

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MM: FARMACOLOGIA GENERALE
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General Pharmacology learning is assessed during the written examination of "Physiopathology applied to nursing". The test includes 65 multiple-choice questions (1 correct answer out of 4-5 ). 20 questions concerning the module of Clinical Nursing, and 15 are related to each of the 3 modules General Pharmacology, Semeiotics and Physiopathology and General Pathology . The exam is passed when the student answers correctly to at least 11 questions related to Clinical Nursing and 8 concerning each of the other 3 modules.
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MM: SEMEIOTICA E FISIOPATOLOGIA
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MM: INFERMIERISTICA CLINICA
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MM: PATOLOGIA GENERALE
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Reference books
Author Title Publisher Year ISBN Note
Taglialatela Conforti Cuzzolin Leone Mattioli Moretti Pignataro Vanzetta Farmacologia per le lauree triennali e magistrali II Edizione (Edizione 2) Sorbona 2019
Pontieri GM Patologia e Fisiopatologia Generale per i corsi di laurea in professioni sanitarie (ristampa aggiornata) Edizioni Piccin, Padova 2007
Conforti A., Cuzzolin L., Leone R., Moretti U., Pignataro G., Taglialatela M., Vanzetta M. Farmacologia per le professioni sanitarie Idelson-Gnocchi Sorbona 2015 978-88-7947-592-1
Rossi F., Cuomo V., Riccardi C Farmacologia per le professioni sanitarie (Edizione 1) Edizioni Minerva Medica 2014 9788877117878
Giuseppe Pontieri Elementi di fisiopatologia generale per corsi di laurea in professioni sanitarie (Edizione 3) Piccin 2012
Taylor - Lillis - Lynn Principi fondamentali dell'assistenza infermierisitica (Edizione 8) Piccin 2018
Regueiro Gonzales J.R. Immunologia - Biologia e Patologia del sistema immunitario Piccin 2012
E. Albi, F.S. Ambesi-Impiombato, F. Curcio, B. Moncharmont, A . Palese Le basi cellulari e molecolari delle malattie - per le lauree triennali e magistrali (Edizione 1) Idelson-Gnocchi - Sorbona 2018




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