Bachelor's degree in Biomedical Laboratory Techniques (to qualify as a biomedical laboratory worker) (Verona)

Physical sciences and statistics (2017/2018)

Course code
4S000325
Credits
7
Coordinator
Giuseppe Verlato

Teaching is organised as follows:
Unit Credits Academic sector Period Academic staff
BIOINGEGNERIA ELETTRONICA 2 ING-INF/06-ELECTRONIC AND INFORMATICS BIOENGINEERING TLB LEZ 1ANNO 1 SEM 16-17 Federico Boschi
FISICA APPLICATA A MEDICINA E CHIRURGIA 2 FIS/07-APPLIED PHYSICS TLB LEZ 1ANNO 1 SEM 16-17 Federico Boschi
STATISTICA MEDICA 1 MED/01-MEDICAL STATISTICS TLB LEZ 1ANNO 1 SEM 16-17 Giuseppe Verlato
MISURE ELETTRICHE ED ELETTRONICHE 2 ING-INF/07-ELECTRICAL AND ELECTRONIC MEASUREMENT TLB LEZ 1ANNO 1 SEM 16-17 Roberto Meneghini

Learning outcomes

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MM: BIOINGEGNERIA ELETTRONICA
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Provide an overview of electronic bioengineering with particular reference to applications and biomedical technologies. Acquire the tools to the knowledge of the main laboratory equipment and in particular, the basic concepts of physical quantities and signal processing, transducers and bio-images.
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MM: FISICA APPLICATA A MEDICINA E CHIRURGIA
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The Course is designed to provide the student the basic knowledge of physics, taking particular account of those principles and laws that will be needed to comprehend and to have a deeper understanding of biomedical problems.
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MM: STATISTICA MEDICA
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The course is aimed at enabling the student to: - estimate accuracy and precision of measurements performed in the biomedical field; - properly synthetize and summarize the information collected on a series of patients; - compute the probability of a single event or several events
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MM: MISURE ELETTRICHE ED ELETTRONICHE
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Provide an overview of the basic components and electronic circuits with particular emphasis on applications and references to the equipment used by laboratory technicians and specific emphasis on the chain of detection of physical , electrical transduction , converting them into digital signals .

Syllabus

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MM: BIOINGEGNERIA ELETTRONICA
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A] Basic concepts: from physical quantities to signals. Detection of data Measurements of physical quantities Reduction of noise, filtering Measurement error Accuracy and precision Transducers: static sensitivity, nonlinear characteristics B] Transducers Wheatstone Bridge The diode or thermo-ion valve The triode The transformer Semiconductors, p-n junction. Current in diodes: Graetz bridge, power dissipated The transistor Chemical thermometers The pH-meter The piezoelectric transducer LEDs The laser diode The photodiode The photomultiplier Liquid crystal screens The thermocouple The Peltier cell The Geiger counter The CCD The antennas The resistor The oscilloscope Doppler flowmeters The pulseoximeter C] Bioimaging Ultrasound Nuclear Magnetic Resonance Radiography, Computer Tomography Scintigraphy, Single Photon Emission Tomograpy Positron Emission Tomography Optical Imaging
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MM: FISICA APPLICATA A MEDICINA E CHIRURGIA
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Introduction Physical quantities, Base physical quantities and derived physical quantities. Standards of lenght, mass and time. MKS and cgs systems of units. Cartesian frame of reference. Vector and scalar quantities. Components and magnitude of a vector. Addition and subtraction of vectors. Unit vectors. The scalar products of two vectors. Mechanics Displacement, Velocity, Acceleration. Average and instantaneous velocity. Particle under constant velocity. Average and instantaneous acceleration. Particle under constant acceleration. Forces . The principles of dynamics . Law of universal gravity. Weight. Definition of Work and Energy. Kinetic energy. Work-kinetic energy theorem. Conservative forces. Potential energy. Law of conservation of mechanical energy. Power. Fluids Definition of Fluid. Density. Pressure. Archimede’s principle. Variation of pressure with depth (Stevin’s Law). Pascal’s Law. Measurement of atmospheric pressure or Torricelli’s experiment. Pressure Units: atm, mmHg, Pa. Pressure measurements. Archimede’s principle. Fluid dynamics. Bernoulli’s equation. U-tube manometers. Flow. Measurement of arterial blood pressure. Perfect fluid. Continuity equation for flow and its application to blood circulation. Bernoulli’s theorem and its application to stenosis and aneurysm. Real fluid and viscosity. Blood viscosity. Poiseuille’s Law. Physiological effects of hydrostatic pressure. Thermal phenomena and gases Temperatue, heat. Thermal expansion. Mercury thermometer. Celsius, Kelvin anf Farheneit Scale. Thermal capacity, specific heat. Mechanical equivalent of heat. Gas laws: First and second Gay-Lussac laws. The absolute temperature (Kelvin Scale). Boyle’s law. Avogadro’s law. Ideal gas law. Thermodynamic systems and process. Heat transport by conduction, convection and radiation. Electrical phenomena Electric charge. Coloumb’s law. Electic field, potential energy and electric potential. Electric current. Ohm’s law. Resistance and resistivity. Conductors and insulators. The electronvolt.
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MM: STATISTICA MEDICA
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INTRODUCTION The role of Statistics in Health Professions. DESCRIPTIVE STATISTICS Different measurement scales – Statistical variables and their presentation through frequency distributions: one-entry or double-entry tables – Measures of central tendency: mean (arithmetic, geometric, weighted), median, mode, percentiles – Measures of dispersion: range, interquartile range, sum of squares, variance (mean square), standard deviation, variation coefficient PROBABILITY Classic, frequentist, subjective interpretations of probability – Sum and product rules of probability – Independent and dependent events and conditional probability.
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MM: MISURE ELETTRICHE ED ELETTRONICHE
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Elements of the theory of the measures. Measurement errors. Propagation of errors. Electrical circuits and physical laws in electrical engineering. Characteristics of electrical and electronic components in general. The galvanometer. Measuring instruments and sizes typical of perfusion. Ammeters and voltmeters DC and ca. Definition and purpose of a measure. Fundamentals and derivatives. International System of Units. Fundamental units. Units and samples of the electrical measurements. Systematic errors and accidental; insensitivity instrumental errors. Classification errors. Propagation of the absolute and relative errors of two or more measured physical quantities. Ohm's law; electrical resistance and electrical resistivity. Joule effect and electric power. Equivalent resistance of electric resistors connected in series and parallel. Electromotive Force. Calculation of the current in a circuit. Kirchhoff's laws, definition of electrical network, nodes and branches. Mesh analysis for the calculation of the currents in an electrical network. Definition of electrostatic capacity of capacitors and plans. Equivalent capacitance of capacitors connected in series and in parallel. Definition of magnetic flux. Faraday's law. Electrical inductance. Measurement of voltage and current with amperometric method volts. Galvanometers; Measuring instruments and sizes typical of perfusion. Ammeters and voltmeters DC and ca. Groups and types of transducers and peculiarities of each. Practical applications of calculation of uncertainties and expression of a measurement with electronic or digital devices.

Assessment methods and criteria

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MM: BIOINGEGNERIA ELETTRONICA
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Written exam with to 5-10 exercises (open questions). About 1 hours. No books or notes. Bring calculator and pen.
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MM: FISICA APPLICATA A MEDICINA E CHIRURGIA
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Written exam with to 5-10 exercises (open questions). About 1 hours. No books or notes. Bring calculator and pen.
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MM: STATISTICA MEDICA
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The written examination will consists of about 15 multiple choice questions with 5-8 possible answers, and one exercise on simple data sets. Wrong answers to the written examination will be orally discussed with the student.
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MM: MISURE ELETTRICHE ED ELETTRONICHE
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Written exam with exercises and oral questions with possible interview .

Reference books
Author Title Publisher Year ISBN Note
Jekel JF, Katz DL, Elmore JG, Wild DMG Epidemiologia, Biostatistica e Medicina Preventiva Elsevier-Masson 2009
Swinscow TDV, Campbell MJ Le basi della Statistica per scienze bio-mediche Edizioni Minerva Medica S.p.A., Torino 2004
Lantieri PB, Risso D, Ravera G Statistica medica per le professioni sanitarie (Edizione 2) McGraw-Hill, Milano 2004
Fowler J, Jarvis P, Chevannes M Statistica per le Professioni Sanitarie EdiSES srl, Napoli 2006
Verlato G, Zanolin ME Esercizi di Statistica Medica, Informatica ed Epidemiologia Libreria Cortina Editrice, Verona 2000




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