Combined Bachelor's + Master's degree in Medicine and Surgery

Genetics and Molecular Biology - BIOLOGIA MOLECOLARE

Course code
Name of lecturer
Donato Zipeto
Number of ECTS credits allocated
Academic sector
Language of instruction
Lezioni 1° semestre 2°- 6° anno dal Oct 3, 2016 al Dec 22, 2016.

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Lesson timetable

Lezioni 1° semestre 2°- 6° anno

To view lesson hours, consult* click in order to view the timetable here  

Learning outcomes

To understand the fundamental processes of the science of DNA and the flow of information that leads from DNA to RNA to proteins.
To understand mechanisms, function and regulation of these processes.
To educate medical students to the scientific method through the description of experiments that allowed the elucidation of molecular biological mechanisms.
To understand recombinant DNA technologies and their potential.


• Structure and conformations of DNA
• Complexity of genomic DNA • DNA structure in chromosomes • DNA replication
• DNA repair
• Recombination
• Transcription in prokaryotes and eukaryotes
• Maturation of RNA
• Genetic Code
• Translation
• Regulation of gene expression in prokaryotes
• Regulation of gene expression in eukaryotes
• Degradation and trafficking of proteins
• DNA recombinant technology and recombinant DNA
• Molecular evolution
• An outline of gene therapy

Reference books
Author Title Publisher Year ISBN Note
Amaldi, Benedetti, Pesole, Plevani Biologia Molecolare (Edizione 3) Ambrosiana 2018 978-88-08-18518-1
R. F. Weaver Biologia Molecolare (Edizione 2) McGraw Hill 2009 978-88-386-6507-3
WATSON James D , BAKER Tania A , BELL Stephen P , GANN Alexander , LEVINE Michael , LOSICK Richard Biologia molecolare del gene (Edizione 7) Zanichelli 2015 978-88-08-36480-7
Terry A. Brown Biotecnologie molecolari (Edizione 2) Zanichelli 2017 978-88-08-32096-4 Principi e tecniche utilizzate in biologia molecolare
Brown Genomi (Edizione 3) EdiSES 2008

Assessment methods and criteria

Written test, contextual to the Molecular Biology test, including multiple-choice quiz, open questions and exercises. Subsequent oral test, subject to positive evaluation of the written tests.

Teaching aids



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