Combined Bachelor's + Master's degree in Medicine and Surgery

Immunology

Course code
4S00179
Name of lecturer
Vincenzo Bronte
Coordinator
Vincenzo Bronte
Number of ECTS credits allocated
9
Academic sector
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
Language of instruction
Italian
Period
Lezioni 2° semestre 1°- 5° anno dal Feb 20, 2017 al May 26, 2017.

Lesson timetable

Lezioni 2° semestre 1°- 5° anno

To view lesson hours, consult* click in order to view the timetable here  

Learning outcomes

Objectives of the course
• acquisition of the knowledge in fundamental biologic mechanisms regulating the immune system function for the defense against infections, as well as pathogenesis of hypersensibility, autoimmunity and immunodeficiency; 

• understanding the main laboratory methods used by the immunologist and the immune pathologist;

Objectives of professional expertise

• overview on the immune system function, either in health or disease state;
• overview on the basics for the most common immune laboratory techniques, with the aim to understand: a) the results of laboratory analyses obtained through immunological techniques; b) previously occurred immune responses to infections; c) congenital or acquired immune dysfunctions; d) hypersensibility patterns; e) main autoimmune pathologies; f) immune strategies applied to allergy and immunodeficiency therapies; g) general principles of vaccine and immune suppression therapy; h) transplantation and tumor immunology.

Syllabus

Innate and acquired Immunity. Anatomy, cytology and biochemistry of the immune system: lymphoid organs, cells (lymphocytes, dendritic cells, macrophages, granulocytes, hemopoietic precursors), and molecules (immunoglobulins, T cell receptor, MHC molecules, co-stimulatory molecules). Cellular receptors of innate immunity, sensing of pathogen and damage patterns. Antigen processing and presentation. Cell-mediated and humoral immune response. The complement cascade. Cytokines, chemokines and cell-cooperation. Defense against infections. Immune tolerance. Hypersensibility reactions. Autoimmune diseases. Immunodeficiency. Immunity and tumors. Principles of immunotherapy. Immuno-hematology. Immunology of transplantation.

Recommended texts:

K. MURPHY, P. TRAVERS, M. WALPORT
Janeway’s Immunobiology
GS Garland Science – 9th edition, 2016

A.K. ABBAS, A.H. LICHTMAN, S. PILLAI
Cellular and Molecular Immunology
Elsevier Saunders, 8th edition, 2015

PETER PARHAM
The immune system
GS Garland Science, - 4th edition, 2015

D. MALE, J. BROSTOFF, D. ROTH, I. ROITT
Immunology
Elsevier, 7th edition, 2009

Assessment methods and criteria

Written test, based on questions with multiple choice answers.

STUDENT MODULE EVALUATION - 2016/2017






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