Bachelor's degree in Nursing (to qualify as a nurse) (Verona)

Pathophysiology applied at Nursing [Matricole pari] - FARMACOLOGIA GENERALE

Course code
Name of lecturer
Roberto Leone
Number of ECTS credits allocated
Academic sector
Language of instruction
INF. VR 1° anno 2° semestre dal Feb 1, 2016 al Apr 8, 2016.

To show the organization of the course that includes this module, follow this link * Course organization

Lesson timetable

INF. VR 1° anno 2° semestre

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Learning outcomes

To understand the basic principles of pharmacokinetics and pharmacodynamics; to understand the drug development process and the Italian pharmaceutical market data; to evaluate the benefit/risk profile of the drugs; to understand the basics of administration and management of drug therapies. To know the main characteristics of antimicrobial and nonsteroidal anti-inflammatory drugs.


1.To understand the general principles of pharmacology; know the main definitions (e.g. drug, medicine, placebo); analysis of the Italian pharmaceutical market (types of prescriptions, bioequivalents and biosimilars, fact sheets and leaflets); analysis of drug consumption (OsMed data); classification of drugs according to the NHS and the International Classification ATC; drug development phases; basic principles to evaluate the efficacy and safety of the drugs; the golden rules for Randomized Controlled Clinical Trials (RCT).
2. To understand the fundamental scientific principles of drug action (pharmacodynamics) and the various mechanisms by which drugs can mediate their pharmacological effect.
3. To understand the fundamental principles of pharmacokinetics those underlie the absorption, distribution, metabolism and elimination of drugs in the body and thereby affect drug effectiveness. To know the main pharmacokinetic parameters, such as half-life, clearance, distribution volume, area under the curve, etc.
4. To understand the main factors which influence the dose and duration of therapy. To apply the rules for dose calculation.
5. To understand the adverse drug reactions (ADRs): classification, mechanisms, characteristics, pharmacovigilance methods, and Italian and European pharmacovigilance laws. Discuss nursing responsibilities with reporting suspected ADRs.
6. Drug-drug interactions: antagonism, synergic action. To understand the influence of self-medication and polypharmacy for the drug-drug interactions.
7. To understand the basic principles of antimicrobial chemotherapy. To know the following terms: spectrum of action, bacterial resistance, bacteriostatic and bactericidal antibiotics. To know the main classes of antimicrobial drugs, particularly their mechanisms of action, therapeutic indications, contraindications and main adverse drug reactions. To know the main characteristics of antitumor agents.
8. To know the nonsteroidal anti-inflammatory drugs (NSAIDs), with particular regard to their mechanisms of action, therapeutic indications, epidemiological data, contraindications and main adverse drug reactions.

Reference books
Author Title Publisher Year ISBN Note
Conforti A., Cuzzolin L., Leone R., Moretti U., Pignataro G., Taglialatela M., Vanzetta M. Farmacologia per le professioni sanitarie Idelson-Gnocchi Sorbona 2015 978-88-7947-592-1

Assessment methods and criteria

Written test. The script consists of a total of 65 questions relating to all teaching modules of the integrated course. The General Pharmacology questions (n= 15) are with multiple choice answers (1 correct between 5). The questions are related to the course program. Each correct answer is worth one point, the test is passed if you reach the minimum overall score of 38 points with a score of at least 11 for Nursing and 8 for the other three modules.

Teaching aids



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