# Bachelor's degree in Obstetrics (to qualify as an obstetrician)

## Biological and physical sciences (2015/2016)

Course code
4S000031
Credits
6
Coordinator
Cristina Bombieri

 Teaching is organised as follows: Unit Credits Academic sector Period Academic staff BIOCHIMICA 3 BIO/10-BIOCHEMISTRY 1°anno 1°semestre Massimo Donadelli FISICA APPLICATA 1 FIS/07-APPLIED PHYSICS 1°anno 1°semestre Federico Boschi BIOLOGIA APPLICATA 1 BIO/13-EXPERIMENTAL BIOLOGY 1°anno 1°semestre Cristina Bombieri GENETICA MEDICA 1 MED/03-MEDICAL GENETICS 1°anno 1°semestre Alberto Turco

## Learning outcomes

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MM: BIOCHIMICA
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Knowing the molecular processes that underlie functions of cell and organism. Knowing how occur the biochemical transformations of metabolism, and how they are regulated. Knowing bioenergetics and metabolism of the cell and of the entire organism.
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MM: FISICA APPLICATA
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Familiarization with the basic concepts of mechanics and fluidodynamics.
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MM: BIOLOGIA APPLICATA
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The course purpose is to provide the basic knowledge about living organism characteristics through the acquisition of the fundamental concepts of functional and molecular principles of cellular processes and of human genetics (mode of transmission of hereditary characters and molecular basis of genetic diseases).
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MM: GENETICA MEDICA
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Basic knowledge of human genetics. Understanding of the principles of hereditary transmission of normal and abnormal traits, as well as the origin of biological hereditary variation.

## Syllabus

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MM: BIOCHIMICA
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MM: FISICA APPLICATA
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Physical quantities, vectors, exercises. Derivative of a function, calculation, examples and exercises. Fermat's theorem and Rolle’s theorem. MECHANICS : Position , displacement , various dimensional motion , rectilinear motion. Average speed and instantaneous speed . Exercises. Acceleration , rectilinear motion uniformly accelerated . Exercises. Laws of Motion ( I, II , III ) .. inertial mass . Weight force . Exercises. Work of a force . Kinetic energy. Kinetic energy theorem . Conservative forces . Potential energy. Gravitational potential energy . Theorem of mechanical energy. Exercises Power . FLUID DYNAMICS : Pressure , density , specific gravity , the law of Stevin , hydraulic press , barometer Torricelli tube manometer open , Archimedes' principle . Exercises. Ideal fluid , stationary bike , motorcycle not turbulent flow . Continuity equation . Venturi . Exercises. Theorem of Torricelli (tank) . Applications . Exercises. Stokes force . Friction in fluids .
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MM: BIOLOGIA APPLICATA
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- Characteristics of the living beings. Symbiosis. Autotrophy and heterotrophy. - Water: characteristics and biological importance. - Eukaryotic and prokaryotic cell: main features and differences. Endosymbiotic theory. Pluricells organisms evolution. - Cell cycle and its regulation, mitosis, meiosis, cell death. Sexual and asexual reproduction. - DNA: structure, function, replication. Organisation of DNA in chromosome. DNA and its role in heredity. Definition of gene. Informational pathway: transcription, RNA maturation, genetic code, translation and protein synthesis. DNA mutation. - Hereditary character transmission and Mendel’s laws. Genetics of blood groups.
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MM: GENETICA MEDICA
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Genomics, Genetics, Epigenetics The human genome. Pedigrees. Mendelian inheritance. Non traditional inheritance. Cytogenetics Standard human karyotype. Anatomy of human chromosomes. Molecular cytogenetics (FISH, aCGH). Numerical and structural chromosome anomalies. Clinical genetics and bioethics Genetic counseling. Prenatal diagnosis. Preimplantation genetic diagnosis (PGD). Genetic testing. Stem cells and regenerative medicine. Bioethic and social issues. Textbook: Dallapiccola e Novelli. Genetica Medica Essenziale, CIC Ed Internazionali, 2012

## Assessment methods and criteria

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MM: BIOCHIMICA
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MM: FISICA APPLICATA
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Written exam with to 5-10 exercises (open questions). About 1 hour. No books or notes. Bring calculator and pen.
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MM: BIOLOGIA APPLICATA
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Written test (multiple choice quiz and open questions) based on the educational content of the course. Contextual to the other teachings of the integrated course.
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MM: GENETICA MEDICA
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Written test contextual to the other teachings of the integrated course.

 Reference books Author Title Publisher Year ISBN Note Roberti, Antognelli, Bistocchi, Talesa Biochimica e Biologia per le professioni sanitarie (Edizione 2) McGraw-Hill 2013 Solomon, Berg, Martin Elementi di Biologia (Edizione 6) EdiSES 2013 Sadava, Hillis, Craig Heller, Hacker Elementi di Biologia e Genetica (Edizione 5) Zanichelli 2019 9788808820655

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