Combined Bachelor's + Master's degree in Medicine and Surgery

Nutritional Epigenomics: a bridge between DNA and disease  (Corso Elettivo)

Course code
DF-0022
Name of lecturers
Simonetta Friso, Patrizia Guarini
Coordinator
Simonetta Friso
Number of ECTS credits allocated
1
Academic sector
MED/09 - INTERNAL MEDICINE
Language of instruction
Italian
Period
Corsi elettivi 2° semestre dal Feb 22, 2016 al May 27, 2016.

Lesson timetable

Corsi elettivi 2° semestre

Not inserted.

Learning outcomes

Main objectives of the teaching course:

After attending the teaching course the student will know:
1) basic knowledge on epigenetics and mechanisms of gene-nutrient interactions affecting epigenetics;
2) main mechanisms through which some nutrients may alter gene expression by modifying epigenetic phenomena;
3) relationships between genes and nutrients and epigenetic mechanisms in major diseases;
4) main strategies on how to approach disease prevention by way of modifying gene expression mechanisms through epigenetics using a correct nutritional approach.

Syllabus

Nutrional epigenetics:
- Introduction and description of the main epigenetic mechanisms
- Folate and epigenetics
- Gene-nutrient interacitons and epigenetics
- Bioactive food compounds and epigenetics
- Methodologies to study epigenetic features of DNA and their link with nutrition with a particular focus on methods to determine global DNA methylation and genome-wide as well as gene-specific methylation.

Assessment methods and criteria

IDONEITY based on participation to the course

STUDENT MODULE EVALUATION - 2015/2016






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