Postgraduate Specialisation in Pathological Anatomy

Course partially running (all years except the first)

Clinical biochemistry and clinical molecular biology 2 (2014/2015)

Course code
4S003331
Credits
5
Coordinator
Gian Luca Salvagno

Teaching is organised as follows:
Unit Credits Academic sector Period Academic staff
DIDATTICA FRONTALE 1 BIO/12-CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY not yet allocated Gian Luca Salvagno
ATTIVITA' PRATICA 4 BIO/12-CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY not yet allocated not yet allocated

Learning outcomes

1.The role of Laboratory Medicine in the diagnostic process and in the monitoring of diseases and drugs. Particular attention will be given to the interpretation of laboratory tests that concern the diagnosis of the main cardiovascular, haematological and metabolic diseases, discussing some clinical cases.
2.The appropriate methodology in the collection and processing of biological samples;
3. The pre-analytical, analytical and post-analytical variables that can influence the reliability of laboratory results.
4) Principal Analytical Techniques of Clinical Biochemistry and Clinical Molecular Biology

Syllabus

Knowledge of the pathophysiological mechanisms and interpretation of laboratory tests related to individual organs and apparatuses, referred above all to the following topics:
• Haemochromocytometric examination,
• Hemocoagulation system,
• Glucose metabolism and diabetes,
• Lipid metabolism, atherosclerotic disease and its complications,
• Acid-base and hydroelectrolytic balance,
• Plasma proteins and inflammation indices,
• Kidney function,
• Liver function,
• Acute myocardial infarction,
• Enzymes in the diagnosis and monitoring of disease,
• Tumor markers,
• Main endocrine abnormalities (thyroid, adrenal gonads, phospho-calcium metabolism),
• Monitoring of pregnancy,
• Applications of molecular biology
• Overview of the main genetic diseases,
• Therapeutic monitoring

Assessment methods and criteria

oral examination

Reference books
Author Title Publisher Year ISBN Note
Carl A. Burtis Edward R. Ashwood, David E. Bruns Tietz Textbook of Clinical Chemistry and Molecular Diagnostics (Edizione 5) Elsevier 2011




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